Search on: PTEN PROTEIN 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   PTEN Phosphohydrolase 
Descriptor Spanish:   Fosfohidrolasa PTEN 
Descriptor Portuguese:   PTEN Fosfo-Hidrolase 
Synonyms English:   MMAC1 Protein
Mutated In Multiple Advanced Cancers 1 Protein
PTEN Phosphatase
PTEN Protein
PTEN Protein Phosphatase
Phosphatase and Tensin Homologue on Chromosome Ten Protein
Phosphatase, PTEN
Phosphatase, PTEN Protein
Phosphohydrolase, PTEN
Protein Phosphatase, PTEN  
Tree Number:   D08.811.277.352.650.850
D12.776.476.590
D12.776.624.776.695
Definition English:   A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION. 
History Note English:   2006(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50580 
Unique Identifier:   D051059 

Occurrence in VHL: 		 

Similar:
  
DeCS CID-10 SciELO LILACS LIS